Endocrine Abstracts

The introduction of PCSK9 inhibitors has changed the paradigm of dyslipidemia treatment. These monoclonal antibodies produce an incremental LDL reduction of about 60% add-on current therapy. Achieving LDL concentrations below 40 mg/dl is usual. The recent publication on the effect of very low LDL concentrations on atherosclerotic plaque burden (Glagov study) and on cardiovascular outcomes (Fourier and Spire) show the impact of this therapy in cardiovascular prevention. In the ...